Denver Broncos 21–17 Philadelphia Eagles

Bo Nix threw an 11-yard touchdown pass and JK Dobbins rushed for a two-yard score in the fourth quarter as the Denver Broncos wiped out a 14-point deficit to hand the Philadelphia Eagles their first loss of the season. The Broncos batted down Jalen Hurts’ last-gasp pass on the final play of the game to send the Super Bowl champions to just their second loss in their last 22 games. The Broncos (3-2) caught a huge break in their rally when the Eagles had a late fourth-down conversion called back on an illegal shift penalty whistled against running back Saquon Barkley.

Houston Texans 44–10 Baltimore Ravens

CJ Stroud threw for 244 yards and four touchdowns, and Houston (2-3) strolled to a 44-10 win over a depleted Baltimore team, matching both the most lopsided road win in Texans’ history and the most lopsided home loss in Ravens’ history. Baltimore (1-4) were without two-time MVP quarterback Lamar Jackson, and that was far from their only problem. Defensive standouts Kyle Hamilton, Roquan Smith and Marlon Humphrey all missed the game, and the Ravens already were weakened on that side of the ball because of a neck problem that ended Nnamdi Madubuike’s season. Baltimore were also without All-Pro fullback Patrick Ricard and tackle Ronnie Stanley.

New England Patriots 23-20 Buffalo Bills

Drake Maye led the Patriots on a 37-yard drive to set up Andy Borregales’ 52-yard field goal with 15 seconds left, and New England beat the Buffalo Bills (4-1), leaving the NFL without an undefeated team five weeks into the season. Stefon Diggs had 10 catches for 146 yards for the Patriots (3-2) in his first game at Buffalo since the Bills traded him to Houston in April of 2024. Rhamondre Stevenson rushed for two touchdowns, the second one set up by Diggs’ 32-yard reception. Maye went 22 of 30 for 273 yards. The Patriots have a winning record through five games for the first time since 2019.

Washington Commanders 27–10 Los Angeles Chargers

Jacory Croskey-Merritt scored two touchdowns, and the Washington Commanders (3-2) rallied from a 10-point deficit after forcing a big fumble in the second quarter to score 27 straight points and beat the Los Angeles Chargers (3-2). Washington’s Jayden Daniels was 15 of 26 for 231 yards and a touchdown after missing two games with an injured left knee. The Chargers were one of the least penalized teams in the first three weeks of the season, when they were 3-0. But they were done in by sloppy play last week, with 15 penalties for 107 yards in a 21-18 loss at the New York Giants. Back home at SoFi Stadium, it happened again. They had 10 penalties for 85 yards and three turnovers in Washington territory.

Las Vegas Raiders 6–40 Indianapolis Colts

Jonathan Taylor ran for three touchdowns and a two-point conversion, and Daniel Jones threw two touchdown passes as the Indianapolis Colts routed the Las Vegas Raiders. The 34-point margin was Indy’s largest since 2013. Jones finished 20 of 29 for 212 yards and moved to 4-1 as a starter this year, surpassing his combined victory total over the past two seasons with the New York Giants. Taylor rushed 17 times for 66 yards and caught three passes for 20 yards. The Colts converted a blocked punt, two interceptions and a turnover on downs into TDs. Las Vegas fell to 4-1.

Tampa Bay Buccaneers 38–35 Seattle Seahawks

Lavonte David intercepted Sam Darnold with 58 seconds left and Chase McLaughlin kicked a 39-yard field goal as time expired to give the Tampa Bay Buccaneers (4-1) a thrilling win over the Seattle Seahawks (3-2). Baker Mayfield tied it for the Bucs with an 11-yard touchdown pass to Sterling Shepard with 1:08 left, and the Seahawks took over with the chance to drive for the winning score. But David’s pick on a deflected ball negated the need for any further heroics by Mayfield. He threw for 379 yards and two touchdowns, and Darnold threw for 341 yards and four TDs.

Detroit Lions 37–24 Cincinnati Bengals

David Montgomery ran for a touchdown and threw for one on a trick play in his hometown and the Detroit Lions (4-1) rolled to their fourth straight win, this time over the reeling Cincinnati Bengals (2-3). Jared Goff threw three touchdown passes for the Lions. Montgomery, a seven-year veteran, had passing and rushing scores in a game for the second time. He played quarterback at Cincinnati Mt Healthy High School and had more than 20 friends and relatives at the game. The Bengals have dropped three straight by a combined total of 113-37 since star quarterback Joe Burrow suffered a toe injury during a win over Jacksonville.

Dallas Cowboys 37-22 New York Jets

Dak Prescott threw four touchdown passes, leading the Dallas Cowboys to an easy victory over the New York Jets. Dallas scored on two 90-yard drives in the second quarter, despite missing four starters on the offensive line. Javonte Williams ran for 135 yards and a touchdown and also caught a TD pass. The Cowboys, now 2-2-1, bounced back from a 40-40 tie against Green Bay last week. The Jets remain winless at 0-5 in Aaron Glenn’s first season as head coach.

Tennessee Titans 22–21 Arizona Cardinals

Cam Ward throws for a career-high 265 yards, leading the Tennessee Titans to an improbable victory over the Arizona Cardinals. The Titans snap a 10-game losing streak with a dramatic fourth-quarter comeback. The Cardinals led 21-6 in the fourth quarter but made crucial mistakes. Emari Demercado dropped the ball before crossing the goalline, resulting in a fumble. The Titans capitalized, scoring a touchdown. Later, Dadrion Taylor-Demerson intercepted a pass but fumbled, allowing the Titans to score again. Joey Slye’s 29-yard field goal sealed the win. Calvin Ridley had five catches for 131 yards.

Minnesota Vikings 21–17 Cleveland Browns

Vikings receiver Jordan Addison caught a 12-yard touchdown pass from Carson Wentz with 25 seconds left to give Minnesota victory over the Cleveland Browns at London’s Tottenham Hotspur Stadium. The 10-play, 80-yard drive gave the Vikings (3-2) a much-needed win on their historic international road trip, which started with a 24-21 loss to the Steelers in Dublin last week. It also spoiled Dillon Gabriel’s first NFL start, as the Browns rookie put his team (1-4) in position to win by throwing two touchdown passes. Fellow rookie Quinshon Judkins rushed for 110 yards on 23 carries. Wentz shook off a shoulder injury that briefly sent him to the locker room and led two scoring drives in the second half.

Miami Dolphins 24-27 Carolina Panthers

Bryce Young threw for two touchdowns and Rico Dowdle ran for 206 yards and a touchdown as the Carolina Panthers rallied past the Miami Dolphins in Charlotte. Young’s short pass to rookie tight end Mitchell Evans with 1:59 to play gave the Panthers (2-3) the lead for good as they matched the largest comeback to win a game in franchise history by overcoming a 17-point hole. Young had a horrific first quarter, but he ended up 19-for-30 passing for 198 yards with an interception. Dowdle, filling in for injured Chuba Hubbard, did his work on the ground on 23 carries, coming up four yards shy of matching the single-game franchise rushing record. Miami’s Tua Tagovailoa completed 27 of 36 throws for 256 yards with three touchdowns and Jaylen Waddle gained 110 receiving yards on six catches and scored a touchdown, but the Dolphins (1-4) dropped to 0-3 in road games.

New York Giants 14–26 New Orleans Saints

Spencer Rattler passed for an 87-yard touchdown to Rashid Shaheed, safety Jordan Howden returned a fumble 86 yards for a score, and New Orleans defeated the turnover-prone New York Giants for the Saints’ first victory under rookie coach Kellen Moore. Rattler earned his first victory in 11 career starts, passing for 225 yards without a turnover. Giants rookie QB Jaxson Dart, who won his first career start last week, passed for 202 yards and two touchdowns, but also turned the ball over three times. New York turned the ball over five times in all, none more costly than when Bryan Bresee stripped running back Cam Skattebo, leading to Howden’s TD. Both teams are 1-4.